Consulation with Dr. Herman

On December 28 we went to Johns Hopkins to meet with Dr. Herman. Dr. Herman is a radiation oncologist at Johns Hopkins. He and his resident Dr. Fox have been really helpful and accessable since we met them in the hospital after my mother's Whipple procedure. Dr. Herman seems like the kind of guy you could easily go and grab a beer with.

My mother had her first post-operative CT scan and bloodwork done in the morning at the Weinburgh building. We met Dr. Herman and Dr. Fox afterwards. As usual, he was really helpful:

• He mentioned Hopkins had participated in the VMP trial but stopped after 4 patients because the coordinator quit and it was a high maintenance trial. Of the 4 patients, 2 were still completing the trial but the other 2 had already had recurrance. One of the knowledgable nurses mentioned the VMP seemed to be about twice as hard as the normal regimen but that people had recovered very well a month after the intensive part was completed.
• Herman recommended talking directly with Dr. Laheru regarding the treatment plan to be offered by Hopkins. We had finally set up an official consultation with Dr. Laheru so we would just wait to see him then.

Dr. Herman sent me the results of the CT and bloodwork later. Mom's CT scan was clean and her CA 19-9 dropped to about 15.7 which was well within normal range. Great news! (Although this doesn't mean the cancer is gone).

Christmas

The whole family got together for Christmas. Although Mom had one bout of vomiting after we saw Dr. Cameron on the 21st she had felt better from the 24th just in time to celebrate Christmas!

Follow Up with Dr. Cameron

On December 21 we went for our 2 week follow-up visit with Dr. Cameron. My mother had bought him a scarf and she had bought a pen for Dr. Meneshian (Dr. Cameron's fellow). Grace had gone through a fair amount of pain buying and returning things and working with my Mom over the phone from the mall while they finalized what to get.

We arrived at 1pm and ended up waiting 2 hours to see him. We realized that Dr. Cameron has the following brilliant (for him) scheduling strategy: Tell all patients to arrive at exactly the same time (1pm) and then it's first come first serve to see him. I suspect he does this so that he maximizes the use of his time and because he can (he is one of the best surgeons in the world). I doubt any of his patients complain. He came in and looked at my mother's incision and said: "Your incision looks great - you must have had an excellent surgeon". I bet he says that to all his patients :->.

We asked him about his recommendation for adjuvant therapy and he confirmed what we were thinking. He mentioned that the two "bright spots" in this area are Dr. Picozzi's Virginia Mason Protocol and Dan Laheru's vaccine. He had mentioned though that the VMP was very toxic and that he wouldn't hesitate to send somebody to Seattle if they were in their 50s. But he said we should definitely still see Dr. Picozzi since I told him we already had an appointment lined up. My Mom, who has been really scared of chemotherapy and radiation has clung to those words in defense and has kept repeating that the VMP is for younger people. We've asked her to keep an open mind and wait to talk to Dr. Picozzi.

Next came the all important gift giving portion of the visit. My mother gave Dr. Cameron the gift and asked him to give the pen to Dr. Meneshian. She was really worried because she originally got the pen for Dr. Cameron and the scarf for Dr. Meneshian. But my father remembered that Dr. Cameron already had a really fancy nice pen so she decided to switch them. However, the pen was more expensive than the scarf and my mother was really worried for the next few days that somehow Dr. Cameron would figure it out and get upset. My mother tends to worry a lot about these kinds of things.

In retrospect, we're really thankful that we were able to have Dr. Cameron handle my mother's Whipple procedure. This is probably among the most difficult procedures and Dr. Cameron has done more of these than anybody alive. He was chief of surgery at JHH. Dr. Marshall called him "The Master". Dr. Picozzi called him "The best surgeon in the world". An ICU nurse mentioned the ICU was getting full and they were moving patients out but my Mom was OK since she was Dr. Cameron's patient. Another nurse mentioned that none of Dr. Cameron's patients are supposed to get infections or complications so they work very hard to avoid them. He puts many of his patients in beautiful Marburg. And most importantly, there is a huge imposing painting of him in the lobby of Blalock.

Mom loves telling people we had the best surgeon in the world and that we stayed on the same floor with famous people and an Arab prince. I think we all derive a lot of psychic benefit from that.

The Dream

My mother had been feeling miserable with nausea and vomiting since the Whipple procedure. On the 19th she took a nap and woke up from a very interesting dream. She said she dreamed that she was going to the bathroom (#2) and that lots of stuff was going down (as she described it). She woke up feeling a lot better and this marked a huge turning point in her recovery!

Consultation with Dr. Marshall

My sister Grace had heard about Dr. Marshall through a business contact. He is a famous professor/oncologist at Georgetown's Lombardi Cancer Center. Georgetown is about 45 minutes from my parent's place so it is one of the "local" oncologist options. In the morning prior to leaving, my mother had a terrible sharp pain in her stomach. I was worried she wouldn't make it but she took some Malox and somehow she found the strength to go with us. We were anxious for her to come with us because we didn't want to miss this opportunity to talk to Dr. Marshall.

Dr. Marshall and his assistant Dr. Amy Rankin were extremely nice. They made us feel very well taken care of which was a nice contrast to relying on the surgeons. Dr. Marshall was very concerned about my Mother's condition and prescribed some IV fluids. A blood test revealed her potassium was very low so they also infused some potassium. He prescribed a lot of medication to help my mother feel better including fentanyl patches (better to control pain than using oral meds if you are vomiting), potassium supplements, an anti-nausea steroid, etc. It's a good thing my mother went to see Dr. Marshall that day because she was really dehydrated and the IV fluids made her feel a lot better. One advantage of seeing an oncologist early on after the Whipple is that you have somebody who can prescribe meds and take care of you. We really liked Dr. Marshall because he paid a lot of attention to my mother's comfort.

We also discussed his take on adjuvant therapy. His philosophy boils down to starting with chemotherapy using Gemcitabine. Radiation would only possibly come later on after several months. He also believes in long term maintenance using a low dose of some medication (I forget which). To support his approach he referred to the European study which showed that radiation was of questionable benefit and that chemotherapy alone proved superior. The Hopkins doctors had discounted this study saying that the radiation may not have been applied effectively. Dr. Marshall also believes that it is more important to focus on treating "systemically" to prevent distant metastasis first rather than treating locally to prevent local advance. The reason he presented is that the distant metastases are what kill you. His take on the Hopkins approach was that they had a very strong radiation oncology department so this explains why it would figure prominently in the treatment plan. We also asked him about his opinion on the Virginia Mason protocol. He said that it was a single institution study that hadn't been verified and that there was a tradeoff with the significantly higher toxicity.

So the plot thickened now with three major options on the table:

• Hopkins approach: radiation w/ Xeloda followed by chemo w/ Gemcitabine (maybe Tarceva)
• Georgetown approach: chemo w/ Gemcitabine maybe followed later with radiation.
• Virginia Mason approach: radiation w/ 5FU/Cisplatin/Interferon followed by Gemcitabine (maybe Erbitux)

BTW - the cafeteria at Georgetown was excellent. It's across from the Lombardi Center.

Harassing the Surgeons

I definitely wore out my welcome with the GI Gold oncall team at JHH. They had given me a sheet that said to call if my mother experienced nausea, vomiting, fever, etc. So I dutifully called every time she vomited (which was really frequent for the first 2 weeks after the Whipple). At first they would return my calls fairly regularly. After about a week though, I never heard back from them. I suppose I got blacklisted.

Also, I had been calling Dr. Cameron's assistant Bonnie periodically to ask for appointments, prescriptions and other misc. things. She was also our first point of contact when my mother had an issue during business hours. One morning, at around 6 am I called because my mother had vomited a lot. In the past, when Bonnie was not around, Cameron's line would be routed to some other assistant who would cover for her. So this morning, when a man answered the line, I asked for Bonnie and he gruffly answered: "If you call back at 8:30, you can talk to Bonnie". Then he proceeded to quickly hang up before I had a chance to say anything. As I hung up, it dawned on me that that was Dr. Cameron! He had never answered his line before so I just found it completely unexpected that he would be picking up on his own phone line.

I think it's best overall not to rely too heavily on the surgeons for post-operative care. They are more than happy to hand you off to somebody else. It's probably a good idea to build a relationship early with an oncologist or other kind of doctor who can care for the patient. I understand it too - they are too busy doing surgery.

Post-Whipple Misery

The day my mother was discharged she felt fairly nauseous. We asked for some anti-nausea medication but were told that they don't like to prescribe that as it may mask real problems. Once we got home things got pretty bad. For about two weeks my mother could barely get out of bed because of nausea. Every few days she would vomit what seemed like all the fluids and food she had managed to get down for the last few days. We were really worried that there was some kind of blockage. At one point Dr. Meneshian was ready to re-admit my mother but we heard the next day that Dr. Cameron had nixed that idea. At least he prescribed metoclopramide which seemed to help with the nausea.

My father also went through a lot trying to keep my mother comfortable. For example, he had to really strive to meet my mother's extremely exacting standards for food preparation. Eventually, he resorted to bringing the ingredients up to her and letting her determine how much of each to add so that she would not be able to accuse him of adding too much or little of something.

Consultation with Dr. Patel

My sister Grace and I went to visit Dr. Patel, an oncologist in Fairfax. This was our "very local" oncologist option because she's about 20 minutes from our parent's house. My mother was unable to go because she was feeling so ill. When we showed up without the patient they were a little confused but we were able to eventually see Dr. Patel. Dr. Patel was very kind and explained things very nicely to us. She offered the standard treatment of radiation with Xeloda followed by chemotherapy with Gemcitabine. We asked her about the VMP and she rated the VMP as an 8 out of 10 on the difficulty scale whereas the standard treatment was a 2.

Next Steps and Adjuvant Therapy

So far, everything was going as well as it could go I suppose. We felt lucky that our Mother was able to have the Whipple and that her path report came out reasonably good. However, the odds are very high for a recurrance with surgery alone. The stats seem to indicate an 80-90% recurrance rate for surgery alone. Now we started to investigate the different adjuvant treatments available.

This part was very confusing. We spent a lot of time on the web and also calling up different institutions that were running clinical trials. One survivor from the Hopkins message board was also very kind to share her experiences with the Virginia Mason Protocol. The two things that stood out in our research were Dr. Picozzi's Virginia Mason Protocol and the Hopkins GVAX Vaccine. Both of these treatments have had very interesting preliminary results from single institution trials. Standard treatment seems to provide overall 5 year survival rate of about 15-20%. Johns Hopkins has data showing that resected patients without spread have 5 year survival of 40%. I'm not sure if my mother falls into that category. The Virginia Mason Protocol (VMP) shows an overall 5 year survival rate of about 45-50%. The patients in the study also mostly had poor pathology reports so that seemed pretty impressive. The Hopkins Vaccine showed 1 and 2 year survival at rates even better than the VMP. The downside that we have heard about the VMP is that it is very toxic and difficult to get through. The downside with the GVAX vaccine is that it does not seem to be available at the moment. The other two drugs that sounded interesting were Avastin and Tarceva. Both of these have had some success with treating advanced pancreatic cancer and are currently in testing for adjuvant therapy.

The Hopkins oncologists were recommending what I consider fairly standard treatment. They recommended radiation with Xeloda followed by chemotherapy using Gemcitabine. We could participate in a trial to add Tarceva as well.

We decided to set up appointments with oncologists at Georgetown, Johns Hopkins, Virginia Mason and locally at Fairfax. It was time to go oncologist shopping.

Our mother has been very anxious about the chemo plan. But she's preparing herself and has already bought a very nice wig.

Recovering at the Marburg Pavilion

One really nice thing about being a patient of Dr. Cameron is that his patients are sometimes put in the Marburg Pavilion (I'm not sure if this happens all the time though and probably depends on availability). Marburg is the luxury section of the hospital and it really is beautiful. There are hard wood floors and lots of wood paneling. The nurse staff is really kind and attentive. There's also a very comfortable guest room with couches, a TV, coffee, tea, snacks and most importantly a computer. I did a lot of research on adjuvant therapy on the computer. While we were there we saw a very famous celebrity and also an arab prince with his entire entourage!

My Mom seemed to recover quite quickly while we were in the hospital. She was doing well with her breathing exercises and walking (which is very important). She had started to eat a little bit of solid food after several days. Her biggest problem was nausea but they kept that under control with some medication.

Dr. Cameron is a very early riser. He would usually come by around 5:30 am to visit my Mother. He would breeze in and generally say to my Mother - "You're doing great" and breeze out. Sometimes he would be with Dr. Meneshian and some other fellows or residents. During my Mother's stay, Dr. Cameron left to go to a conference. When Dr. Cameron was not around I noticed that Dr. Meneshian would do his rounds at around 9am. I'm sure it's nice to have a break when the boss goes out of town.

Pathology Report

After the Whipple, we waited anxiously to hear about my mother's pathology report. They take all the removed tissue to the lab and perform tests on it to see how well the surgery was done and whether there was any spread. Getting the results is a pretty scary moment because this will give you an idea of how advanced the cancer is. On Dec. 2 we finally got the results.

• 3.5 cm tumor on pancreatic head of type ductal adenocarcinoma
• moderately differentiated
• lymph nodes negative for tumor
• margins negative for tumor
• perineural invasion present

I think this put her at a Stage IIB which was better than we originally thought. We were relieved to hear the margins were clean and that the lymph nodes were negative. However, the size of the tumor, nerve spread and moderate differentiation are not good.

The Whipple Procedure

This is our family the day before my mother's Whipple.

Dr. Cameron scheduled my mother's Whipple Procedure for November 29, 2005. My sister Linda said "pancreaticoduodenectomy" to Dr. Cameron and he was very impressed. I'm sure the surgeons and oncologists have a good time hearing people mispronounce all the crazy procedure and drug names. The Whipple itself is very complicated. It can take anywhere from 6 to 10 hours.

My mother was really scared about the surgery and mentioned several times that this whole thing seemed like a dream.

They took my mother away at around 6 am and the family walked with her to the Weinburgh building. We were able to stay with her for a bit while they prepped her for surgery and we met the anesthesiologist who was very kind. Around 7:30am she was off to the OR and we were sent to the waiting room. The Weinburgh waiting area is really nice. There are comfortable couches and TVs around.



They told us that the OR nurse was going to call us every hour or so to give us an update on how things are going. The first update came around 8:30am. The nurse said that my mother was doing fine and that she would call again in about an hour or so unless the operation was over in which case Dr. Cameron would come speak to us. We knew that it would be very bad if Dr. Cameron came out early as that probably meant that they had aborted the Whipple. It's only after they open up the patient when they make the final determination if the tumor is resectable. So the next phone call was nerve racking. At 10:10am the nurse called again and we all looked at each other since nobody really wanted to take it. My sister Linda went to take the call. When she was on the phone she looked upset so I was really worried. But she came back and said that everything was going fine and they were going to proceed with the Whipple! We were all unbelievably relieved.

After about 6 hours into the surgery Dr. Cameron came out and found us. He was in his green surgical outfit. He said that everything went very well and that as far as he could tell they had removed the entire tumor. I guess they do some pathology tests as they are removing the tumor to ensure that everything was removed. He said they removed about 1/3 of my mother's pancreas and about 1/3 of her stomach. We thanked Dr. Cameron profusely. We were told we could see our Mother in the ICU in a few hours after they closed her up.

My mother spent two nights in the ICU. When we first saw her she was in a lot of pain and also was suffering from a lot of nausea. We had one big scare where her hemoglobin levels were very low and they thought that it was either a faulty test or that it could be internal bleeding. The surgeons were ready to go back in if it was the latter case. Thankfully, the test turned out to have been wrong and a different kind of test confirmed her levels were OK. By the third day she was actually looking reasonably good and we were all happy that she was doing so well.

Consultation with Dr. Cameron

I called Dr. Canto's assistant on Monday to make sure she had done the referral to Dr. Cameron. Bonnie, Dr. Cameron's very nice and helpful assistant called me early Tuesday to schedule. She mentioned that Dr. Cameron's first available appointment was on November 29. I mentioned that we were feeling under some time pressure since diagnosis was so late and asked if there was anything that might open up earlier. She said she would check and call me back later in case there was a cancellation. Bonnie called back around 10 am and mentioned we could see Dr. Cameron today! I learned that it always helps to push and be creative with respect to scheduling - there are often cancellations or other ways to expedite getting an appointment.

Mom, Dad, Grace and I drove back over to JHH for our second visit. Dr. Cameron sees patients at the outpatient center across from the McEldery garage. It was very empty in the waiting room probably due to the holidays. We waited in the examination room and Dr. Cameron came in and introduced himself. He went over my Mom's history with her and she mentioned that she was shocked and never expected this to happen to her. He said that nobody ever does. She asked if there was any hope and he replied: "Sure, there's hope!". We had a really great impression of Dr. Cameron - he seemed very confident and very sharp which was exactly what we wanted to see.

Dr. Cameron looked over her file and said she was a candidate for the Whipple! He said: "How about next Tuesday?". I was unbelievably relieved to hear this. On the other hand I think we were all stunned that scheduling it could be so simple and that it would happen so soon. So we went back home to spend the week together and prepare for the surgery. My father mentioned that we should pray that Dr. Cameron would not have some kind of stressful Thanksgiving family reunion and that he would come back relaxed and well rested for our mother's surgery.

EUS and CT Scan with Dr. Marcia Canto

Dr. Canto is a screening specialist for pancreatic cancer. She is from the Philippines and graduated from the University of the Philippines. We immediately felt a connection to her because our family lived for many years in Manila.

We arrived at JHH on the morning of the 18th and went to the 5th floor of Blalock. My mother had the EUS (Endoscopic Ultrasound) and was very nauseous after the procedure. They had given her morphine for pain and she really didn't react well to this. We then went to the basement for her CT scan and returned to wait to hear from Dr. Canto. Prior to the procedure Dr. Canto had asked my mother about her symptoms. She then mentioned not to worry about the procedure and that perhaps it was not even cancer. I think my mother secretly clung to this hope as we patiently waited for Dr. Canto to arrive with the results.

We waited a long time in a small consultation room and I was worried that this meant bad news. Dr. Canto finally arrived and confirmed that it looked like pancreatic cancer (adenocarcinoma). She mentioned the tumor was about 3.5 cm - larger than we had originally thought. However, she added that the cancer looked resectable which is excellent news as far as these things go. We told her we had already been in contact with a Hopkins surgeon but we asked her who she would recommend. She said: "If it was my mother, I would go with Dr. Cameron". In our initial discussions with the Hopkins surgical assistants, we had heard that once you choose a surgeon you cannot switch. We mentioned this to Dr. Canto and she said it was not a problem and that it happens all the time. She said she would refer us to Dr. Cameron! That was great news and we were happy with that decision. As Dr. Canto departed, Grace said "Salamat Po" which means "Thank You" in Filipino. Although my mother felt really nauseous all day, I think we felt guardedly optimistic that my mother could have the Whipple procedure.

On Monday, Dr. Canto's very kind assistant faxed over a copy of my mother's reports and confirmed that she had referred us to Dr. Cameron. Her CA 19-9 was 801.7. We also received the CT results which stated:

Large mass in head of pancreas consistent with pancreatic cancer with dilated pancreatic duct seen. Tumor appears to extend into the peripancreatic soft tissues. The patient's mass abuts the SMV and the portal vein but there is no definite evidence of invasion seen. Encasement of gastroduodenal artery defined.

1. Mass at the head of the pancreas compatible with pancreatic cancer. Minimal stranding of the mesenteric fat anterior to the mass, suspicious for tumor infiltration. Tumor involvement of the posterior wall of the gastric antrum cannot be excluded.

2. The splenic vein, portal vein, and celiac axis, and SMA are patent. The SMV is patent, but in very close proximity to the mass and possibly minimally compressed.

We weren't sure how to interpret the results but we thought this might put my mother at a Stage III which was worse than we initially hoped for. However, the results seemed to indicate she may still be resectable. In retrospect, going through Dr. Canto for the initial screening and tests was exactly the right thing to do. She had ordered the 3D CT scan (pancreatic protocol) and the EUS and was able to give us a referral to the surgeon we wanted. I believe that any surgeon at the very least would have required a 3D CT scan so going through the screening department first was time not wasted.

I think our mother went through another small bout of depression since we had more results showing that it was pancreatic cancer.

Getting Started

My sisters Linda and Grace had already been starting to do some initial research. Grace, who lives near my parents in Virginia, had spoken to Dr. Hong who wasn't very helpful - he had referred us to a Dr. at Georgetown to do an EUS/ERCP but the tests weren't scheduled till Nov. 22. We looked around and found a lot of information on the web. By far the best resource we found was the Johns Hopkins pancreatic cancer discussion board. There is no better resource than other people who are going through or have gone through this ordeal.

We learned that Johns Hopkins was one of the best places for Pancreatic Cancer which was great because it was located fairly near to my parents. We also saw that surgery was the best hope for treating this disease although only 10-20% of diagnosed patients are eligible for surgery (mostly because of spread or artery/vein involvement). So we began by trying to call the surgeons at Johns Hopkins directly to ask for some advice about how to proceed. I wanted to make sure we had all the right tests lined up to give the surgeons the information they would need to determine if our mother was a candidate for resection. I found it fairly difficult to work directly with the surgery department as a new patient. I heard a lot of conflicting advice from the assistants/nurses. One person said that we may not even need an EUS/ERCP and that the CT may be enough to determine resectability. Another said that we should proceed with the Georgetown tests and only call back after we had the results. I had asked if we could do the tests at Hopkins since I wanted to get in the "system" quickly and she had said that was not possible (this was not true at all). We felt a bit frustrated at this point with the conflicting info and lack of urgency.

So on Monday, Nov. 14 we started driving around to pick up all my mother's records. We picked up a copy of her CT scans and then stopped by Dr. Hong's office to pick up his records. Dr. Hong is a very strange man - we were not with my mother and I think he may have thought we were lawyers because he acted really spooked and was hesitant to give us her records even though I had a note. He wouldn't say anything for many minutes and just stood there - ultimately we got what we needed and drove over to Johns Hopkins. We figured in person was the best way to go. We had asked Dr. Hong if he would do a referral to Dr. Cameron and all he was only willing to write a short note for us.

We had spoken to some Dr. friends and one of them had mentioned Dr. Canto at Hopkins as being a very good gastroenterologist for pancreatic cancer. So we decided to try and find a surgeon to look at our mother's CT scan but also drop off information with Dr. Canto. We got to Hopkins and went to Blalock and walked around the floor where the surgeon's offices were. We ran into an administrator who was really helpful and referred us to one of the surgeons. We had wanted to maybe see Dr. Cameron, but we were introduced to the assistant of another surgeon there. She mentioned that if we went with the other surgeon we couldn't switch later on. So we had to decide if we wanted to try and pursue Dr. Cameron through some other route (he requires a physician referral) or go with this surgeon. We had lunch and called a few people and decided that it would be OK to go with the other surgeon. We left the films with the assistant and then proceeded to the gastro department to leave the records for Dr. Canto. The surgeon's assistant mentioned we would hear the surgeon's initial thoughts on resectability in a couple of days.

Dr. Canto's nurse called us to schedule a 3D CT (pancreatic protocol) and an EUS on Friday the 18th. She mentioned the surgeons would need this data no matter what. We felt somewhat relieved because we were officially in the system at Johns Hopkins and things were finally moving along. We never heard from the surgeon. In retrospect, this all worked out fine and it seems like going through Dr. Canto was the best route to go.

Diagnosis

This is our mother, Kyung Wha Jhong, about a week before her Whipple Procedure. Mom was born on 1/1/1936. She and Dad had just moved to Virginia in February after our father retired from working in Korea. We were happy that they were finally in the US and our family had been planning to celebrate her 70th birthday with a nice trip to Los Cabos, Mexico. Somehow, we always have bad luck with trips to Mexico. On our Dad's 70th birthday we had tried to go to Cancun. But our mother's mother had turned ill and we had to cancel the trip. So this is the second time this has happened and we have decided never to go to Mexico for a family vacation again (bad luck).

Mom had been experiencing stomach pain since April of 2005. This slowly got worse and the pain also spread to her lower back. Her appetite decreased and she lost about 10 or so pounds by the time she was diagnosed in November. We tried early on to prod her to see a Doctor but she was resistant since my father and her were so busy with the relocation. She finally got around to seeing a general practitioner in July who referred her on to Dr. Hong, a gastro doctor. Dr. Hong recommended an endoscopy and a colonoscopy but refused to perform them until my mother received clearance from a heart doctor. She has suffered from some valve problems for many years. So my mother and father had to find a new heart doctor in the area and get a clearance letter. My mother finally had the procedures done in late October and the Doctor said she was very "clean". So my mother asked why she had the pain and she mentioned that a doctor in Korea had thought she might have gallstones. In response to this, Dr. Hong recommended and ordered a CT scan.

The results came back on November 9. I was in Mexico at the time on vacation and my sister Linda called me with the bad news. My radiologist brother-in-law Mike was on the trip with me and mentioned that pancreatic cancer was pretty grim. We found the horrible stats on survival rates for this disease (4% 5-year survival). We were all shocked and felt a lot of sadness that day.